Low-grade serous carcinoma with extensive osseous metaplasia arising from ovarian serous cystadenofibroma
نویسندگان
چکیده
منابع مشابه
Advances in serous tubal intraepithelial carcinoma: correlation with high grade serous carcinoma and ovarian carcinogenesis.
Early serous carcinoma in fallopian tube or serous tubal intraepithelial carcinoma (STIC), an early lesion limited to the epithelium of the fallopian tube and firstly identified from specimen obtained by prophylactic salpingo-oophorectomy, has provided insight into pelvic high grade serous carcinoma (HGSC). Increasing evidence indicates that STIC is a likely precursor for HGSC and several studi...
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A 64-yr-old postmenopausal woman with high-grade squamous intraepithelial lesion and atypical glandular cell of undetermined significance on her Pap test was found to have endometrial serous carcinoma (high grade) involving a polyp in a subsequent endometrial biopsy. She underwent hysterectomy and bilateral salpingo-oophorectomy with multiple biopsies of the peritoneum. Microscopic examination ...
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The fallopian tube is now generally considered the dominant site of origin for high-grade serous ovarian carcinoma. However, the molecular pathogenesis of fallopian tube-derived serous carcinomas is poorly understood and there are few experimental studies examining the transformation of human fallopian tube cells. Prompted by recent genomic analyses that identified cyclin E1 (CCNE1) gene amplif...
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S100A11 is an EF hand-type Ca2+-binding protein involved in various biological processes such as cell proliferation and differentiation. It acts as either a tumor suppressor or promoter in many different types of cancers. Low-grade serous ovarian carcinoma (LGSC) is a less common subtype of ovarian cancer which is considered to develop in a stepwise fashion. To further understand the role of S1...
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Because of the high risk of recurrence in high-grade serous ovarian carcinoma (HGS-OvCa), the development of outcome predictors could be valuable for patient stratification. Using the catalog of The Cancer Genome Atlas (TCGA), we developed subtype and survival gene expression signatures, which, when combined, provide a prognostic model of HGS-OvCa classification, named "Classification of Ovaria...
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ژورنال
عنوان ژورنال: Gynecologic Oncology Reports
سال: 2021
ISSN: 2352-5789
DOI: 10.1016/j.gore.2021.100707